290 Maple Street, Greenville, MO 63944
Acamprosate
- Outpatient Program
- Medication-assisted Treatment (MAT)
- Telehealth
11,500+ federally listed treatment programs · Real Options, Real Recovery
Greenville, Missouri has 1 licensed treatment center. Of those facilities, 1 provide outpatient care options.

Federally listed facilities in Greenville, MO
Federally listed
withdrawal management
24-hour care
incl. IOP
listed in city
in Missouri
Greenville, Missouri treatment center map
1 listings mapped
1 licensed program listed below with addresses, phone numbers, levels of care, and insurance details — compare them and call the center directly.
Showing 1 treatment center in Greenville, Missouri.
290 Maple Street, Greenville, MO 63944
Acamprosate
Statewide data for Missouri
No program in Greenville lists medical detox, so people here usually travel to a nearby city for withdrawal care. The figures below are for Missouri as a whole.
33 of 245 federally listed centers in Missouri (13.5%) report offering medically managed withdrawal, below the national share of 19.6% and 40th of 52 states and territories. The median distance from a community with listed treatment to the nearest detox program is 24.5 miles (farther than the 7.9-mile national median). 5 of 106 measured communities are more than 50 miles from the nearest one.
Read the Detox Access Gap report →Missouri reports 18.86 residential beds per 100,000 residents (1,178 beds at 39 programs) — fewer than the national rate of about 27.0, ranking 40th of 50. Reported occupancy was 100.9%, running near full (national average: 85.1%).
Read the Residential Capacity report →Source: Treatment Locators analysis of federal facility directory and survey data. Figures describe the system as a whole, not any one center — call a center to confirm current services and openings.
Greenville has 1 listed treatment center. These 12 centers are the closest listed options outside Greenville; each is located in the city shown on its listing, with the straight-line distance from Greenville noted below.
14 mi · Piedmont, MO
125 East Green Street, Piedmont, MO 63957
12-Step Facilitation
15 mi · Piedmont, MO
5 Sugar Creek Road, Piedmont, MO 63957
Acamprosate
25 mi · Poplar Bluff, MO
1369 North Westwood Boulevard, Poplar Bluff, MO 63901
Buprenorphine
26 mi · Poplar Bluff, MO
101 South Main Street, Poplar Bluff, MO 63901
12-Step Facilitation
26 mi · Poplar Bluff, MO
686 Lester Street, Poplar Bluff, MO 63901
Acamprosate
28 mi · Poplar Bluff, MO
3150 Warrior Lane, Poplar Bluff, MO 63901
12-Step Facilitation
29 mi · Marble Hill, MO
103 El Nathan Drive, Marble Hill, MO 63764
Acamprosate
29 mi · Marble Hill, MO
208 West Broadview, Marble Hill, MO 63764
Acamprosate
30 mi · Ellington, MO
315 East Walnut Street, Ellington, MO 63638
Acamprosate
32 mi · Fredericktown, MO
309 Garrett Street, Fredericktown, MO 63645
Acamprosate
32 mi · Van Buren, MO
1011 Main Street, Van Buren, MO 63965
Acamprosate
33 mi · Bloomfield, MO
1017 Highway 25 North, Bloomfield, MO 63825
Anger Management
This directory lists 1 licensed treatment programs in Greenville, Missouri, drawn from the federal treatment services record (September 2026). Of those, 1 run outpatient treatment.
Detox manages withdrawal safely and usually lasts a few days to a week; rehab is the treatment that follows, where therapy and medication address the substance use itself. Most people move from detox into inpatient rehab or an outpatient program, and the levels of care guide explains how each step works.
Cost depends on the level of care and how long you stay, and federal parity law requires most plans to cover addiction treatment on the same terms as other medical care. In Greenville, Missouri, 1 of the 1 listed centers report accepting private health insurance and 1 report a sliding fee scale based on income. The federal record lists payment types rather than named carriers, so call the center to confirm your insurance coverage.
Medical detox typically runs three to seven days, residential treatment commonly runs 30 to 90 days, and outpatient treatment can continue for several months. Research summarized by the National Institute on Drug Abuse finds that staying in treatment for at least 90 days across all settings is associated with better outcomes.
Withdrawal symptoms depend on the substance, how much was used, and for how long, and alcohol and benzodiazepine withdrawal can be medically dangerous without supervision. Our withdrawal timeline page sets out what typically happens day by day, and anyone with a history of seizures or heavy daily drinking should speak to a clinician before stopping.
Yes — programs that treat co-occurring disorders address substance use and conditions such as depression, anxiety or PTSD at the same time, which SAMHSA identifies as the recommended approach. You can filter this directory for dual diagnosis treatment to see which Greenville, Missouri programs report providing it.
Understand your options before you call a treatment center.