130 Industrial Drive, Suite 130, Greenville, SC 29607
12-Step Facilitation
- Medical Detox
- Residential Treatment
- Medication-assisted Treatment (MAT)
11,500+ federally listed treatment programs · Real Options, Real Recovery
Greenville, South Carolina has 7 licensed treatment centers. Of those facilities, 3 offer 24-hour inpatient or residential rehab programs, 3 offer confirmed medical detox, 6 provide outpatient care options, and 4 provide intensive outpatient (IOP) services.

Federally listed facilities in Greenville, SC
Levels of care in Greenville
Federally listed
withdrawal management
24-hour care
incl. IOP
listed in city
in South Carolina
Greenville, South Carolina treatment center map
7 listings mapped
7 licensed programs listed below with addresses, phone numbers, levels of care, and insurance details — compare them and call the center directly.
Showing 7 treatment centers in Greenville, South Carolina.
130 Industrial Drive, Suite 130, Greenville, SC 29607
12-Step Facilitation
6 Dunean Street, Greenville, SC 29611
12-Step Facilitation
47 Fisherman Lane, Greenville, SC 29615
12-Step Facilitation
157 Brozzini Court, Suite C, Greenville, SC 29615
Methadone
602 Airport Road, Suite C, Greenville, SC 29607
Buprenorphine
16 Mills Avenue, Suite 8, Greenville, SC 29605
12-Step Facilitation
1400 Cleveland Street, Greenville, SC 29607
12-Step Facilitation
Statewide data for South Carolina
Greenville has 3 listed programs offering medical detox. The figures below are for South Carolina as a whole.
18 of 93 federally listed centers in South Carolina (19.4%) report offering medically managed withdrawal, close to the national figure and 19th of 52 states and territories. The median distance from a community with listed treatment to the nearest detox program is 20.4 miles (farther than the 7.9-mile national median).
Read the Detox Access Gap report →South Carolina reports 8.09 residential beds per 100,000 residents (443 beds at 14 programs) — fewer than the national rate of about 27.0, ranking 50th of 50. Reported occupancy was 90.7%, running near full (national average: 85.1%).
Read the Residential Capacity report →Source: Treatment Locators analysis of federal facility directory and survey data. Figures describe the system as a whole, not any one center — call a center to confirm current services and openings.
This directory lists 7 licensed treatment programs in Greenville, South Carolina, drawn from the federal treatment services record (September 2026). Of those, 3 provide medical detox, 3 offer inpatient rehab or residential treatment and 6 run outpatient treatment.
Detox manages withdrawal safely and usually lasts a few days to a week; rehab is the treatment that follows, where therapy and medication address the substance use itself. Most people move from detox into inpatient rehab or an outpatient program, and the levels of care guide explains how each step works.
Cost depends on the level of care and how long you stay, and federal parity law requires most plans to cover addiction treatment on the same terms as other medical care. In Greenville, South Carolina, 7 of the 7 listed centers report accepting private health insurance and 3 report a sliding fee scale based on income. The federal record lists payment types rather than named carriers, so call the center to confirm your insurance coverage.
Medical detox typically runs three to seven days, residential treatment commonly runs 30 to 90 days, and outpatient treatment can continue for several months. Research summarized by the National Institute on Drug Abuse finds that staying in treatment for at least 90 days across all settings is associated with better outcomes.
Withdrawal symptoms depend on the substance, how much was used, and for how long, and alcohol and benzodiazepine withdrawal can be medically dangerous without supervision. Our withdrawal timeline page sets out what typically happens day by day, and anyone with a history of seizures or heavy daily drinking should speak to a clinician before stopping.
Yes — programs that treat co-occurring disorders address substance use and conditions such as depression, anxiety or PTSD at the same time, which SAMHSA identifies as the recommended approach. You can filter this directory for dual diagnosis treatment to see which Greenville, South Carolina programs report providing it.
Understand your options before you call a treatment center.