120B O Fallon Plaza, O Fallon, MO 63366
Anger Management
- Intensive Outpatient (IOP)
- Outpatient Program
- Telehealth
11,500+ federally listed treatment programs · Real Options, Real Recovery
249 licensed, federally listed drug and alcohol treatment programs across 108 Missouri cities — 34 with medical detox, 51 with inpatient or residential rehab, and 233 offering outpatient care.

Federally listed facilities in Missouri
Federally listed
across Missouri
withdrawal management
24-hour care
incl. IOP
co-occurring care
Live CDC1,204 drug overdose deaths in Missouri for the 12 months ending April 2026, 9.7% lower than a year earlier. See national and state trends.
Of the 249 Missouri centers listed, 193 report accepting private health insurance, 143 offer a sliding fee scale, 85 offer payment assistance, and 3 report no charge to the client — as reported to the federal treatment services survey (September 2026). Payment types only; call the center to confirm whether your coverage applies.
Missouri treatment center map
243 listings mapped
Compare addresses, phone numbers, levels of care, and reported payment options — then call the center directly.
13.5%
of centers offer detox
U.S. 19.6%
18.86
residential beds per 100k
U.S. 27.0
120B O Fallon Plaza, O Fallon, MO 63366
Anger Management
1278 West U.S. 40 Highway, Odessa, MO 64076
Acamprosate
704 East Highway 28, Owensville, MO 65066
Acamprosate
1014 West Highway 28, Suite B, Owensville, MO 65066
12-Step Facilitation
1136 South Main Street, Suite #B, Perryville, MO 63775
Acamprosate
406 North Spring Street, Suite 2, Perryville, MO 63775
Acamprosate
125 East Green Street, Piedmont, MO 63957
12-Step Facilitation
5 Sugar Creek Road, Piedmont, MO 63957
Acamprosate
1369 North Westwood Boulevard, Poplar Bluff, MO 63901
Buprenorphine
101 South Main Street, Poplar Bluff, MO 63901
12-Step Facilitation
686 Lester Street, Poplar Bluff, MO 63901
Acamprosate
501 North Sunset Lane, Raymore, MO 64083
Acamprosate
18593 Business Highway 13, Suite 104, Reeds Spring, MO 65737
12-Step Facilitation
11016 State Highway 76, Suite P-31, Reeds Spring, MO 65737
Anger Management
108 West North Main Street, Richmond, MO 64085
Acamprosate
1051 Kings Highway, Suite 5, Rolla, MO 65401
12-Step Facilitation
8 Westbury Drive, Saint Charles, MO 63301
Anger Management
2027 Campus Drive, Saint Charles, MO 63301
12-Step Facilitation
901 Felix Street, Saint Joseph, MO 64501
12-Step Facilitation
4906 Frederick Avenue, Saint Joseph, MO 64506
Acamprosate
2303 Village Drive, Saint Joseph, MO 64506
Buprenorphine
3935 Sherman Avenue, Saint Joseph, MO 64506
12-Step Facilitation
3131 Frederick Avenue, Suite 220, Saint Joseph, MO 64506
12-Step Facilitation
1430 Olive Street, Suite 300, Saint Louis, MO 63103
Acamprosate
From our research
33 of 245 federally listed centers in Missouri (13.5%) report offering medically managed withdrawal, below the national share of 19.6% and 40th of 52 states and territories. The median distance from a community with listed treatment to the nearest detox program is 24.5 miles (farther than the 7.9-mile national median). 5 of 106 measured communities are more than 50 miles from the nearest one.
Read the Detox Access Gap report →Missouri reports 18.86 residential beds per 100,000 residents (1,178 beds at 39 programs) — fewer than the national rate of about 27.0, ranking 40th of 50. Reported occupancy was 100.9%, running near full (national average: 85.1%).
Read the Residential Capacity report →Source: Treatment Locators analysis of federal facility directory and survey data. Figures describe the system as a whole, not any one center — call a center to confirm current services and openings.
If you or someone you love is struggling with drug or alcohol addiction, treatment is available in Missouri. This directory lists 249 licensed, federally listed treatment programs across 108 Missouri cities. Some of these programs focus on alcohol withdrawal, others on opioids, stimulants, or benzodiazepines, and many treat all of them alongside co-occurring mental health conditions.
Care in Missouri spans the full continuum. Of the programs listed here, 34 provide medically supervised detox, 51 offer inpatient or residential rehab, 233 run standard outpatient programs, and 141 run intensive outpatient (IOP) programs. Detox is usually the first step: it stabilizes the body during withdrawal, but it is not a substitute for treatment. Most people move from detox into residential rehab or an outpatient program, where therapy, medication for addiction treatment, and relapse-prevention planning do the longer-term work.
Substance use and mental health problems frequently travel together. 198 Missouri programs in this directory report treating co-occurring disorders such as depression, anxiety, PTSD, or bipolar disorder alongside addiction. Treating both at the same time — rather than one after the other — is the standard recommended by SAMHSA and is a reasonable question to ask any program before admission.
Many Missouri facilities also tailor programming to specific groups. The most commonly reported specialties in the state are adults (202 programs), co-occurring disorders / dual diagnosis (167 programs), and women (122 programs). 6 programs report offering services in Spanish.
Cost is the most common reason people delay treatment. Of the 249 Missouri programs listed here, 193 report accepting private health insurance, 232 accept cash or self-payment, 143 offer a sliding fee scale based on income, and 85 report some form of payment assistance. 3 report providing services at no charge to the client. These figures come from what each facility reported to the federal treatment services survey (September 2026), which records payment types rather than named insurance carriers. Costs and accepted plans are set by each program and change often, so call the facility directly to confirm what it charges and whether your coverage applies.
Learn more: what medical detox involves, levels of addiction care, and withdrawal symptoms and timelines.
This directory lists 249 licensed treatment programs in Missouri, drawn from the federal treatment services record (September 2026). Of those, 34 provide medical detox, 83 offer inpatient rehab or residential treatment and 233 run outpatient treatment.
Detox manages withdrawal safely and usually lasts a few days to a week; rehab is the treatment that follows, where therapy and medication address the substance use itself. Most people move from detox into inpatient rehab or an outpatient program, and the levels of care guide explains how each step works.
Cost depends on the level of care and how long you stay, and federal parity law requires most plans to cover addiction treatment on the same terms as other medical care. In Missouri, 193 of the 249 listed centers report accepting private health insurance and 143 report a sliding fee scale based on income. The federal record lists payment types rather than named carriers, so call the center to confirm your insurance coverage.
Medical detox typically runs three to seven days, residential treatment commonly runs 30 to 90 days, and outpatient treatment can continue for several months. Research summarized by the National Institute on Drug Abuse finds that staying in treatment for at least 90 days across all settings is associated with better outcomes.
Withdrawal symptoms depend on the substance, how much was used, and for how long, and alcohol and benzodiazepine withdrawal can be medically dangerous without supervision. Our withdrawal timeline page sets out what typically happens day by day, and anyone with a history of seizures or heavy daily drinking should speak to a clinician before stopping.
Yes — programs that treat co-occurring disorders address substance use and conditions such as depression, anxiety or PTSD at the same time, which SAMHSA identifies as the recommended approach. You can filter this directory for dual diagnosis treatment to see which Missouri programs report providing it.
All 108 Missouri cities with a listed rehab or detox center.
Understand your options before you call a treatment center.